Masaharu Kotani Selected Research

mannose-6-phosphate

1/2006

Corrective effect on Fabry mice of yeast recombinant human alpha-galactosidase with N-linked sugar chains suitable for lysosomal delivery.

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Masaharu Kotani Research Topics

Disease

6	Fabry Disease (Fabry's Disease) 10/2006 - 12/2002
3	Mucolipidoses (Sialidosis) 03/2007 - 06/2004
2	Neuraminidase deficiency with beta-galactosidase deficiency 04/2006 - 06/2004
2	Carcinoma (Carcinomatosis) 09/2003 - 02/2003
1	Edema (Dropsy) 05/2015
1	Brain Edema (Cerebral Edema) 05/2015
1	Epilepsy (Aura) 05/2015
1	Seizures (Absence Seizure) 05/2015
1	Status Epilepticus (Complex Partial Status Epilepticus) 05/2015
1	Cardiomyopathies (Cardiomyopathy) 10/2006
1	Neuraminidase 1 deficiency 04/2006
1	Lysosomal Storage Diseases (Lysosomal Storage Disease) 04/2006
1	Nonaka type Distal myopathy 04/2005
1	Sandhoff Disease (Sandhoff's Disease) 01/2005
1	Neuroblastoma 07/2004
1	Nervous System Diseases (Neurological Disorders) 01/2004
1	Type I Schindler Disease 01/2004
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2004
1	Neuroaxonal Dystrophies (Neuroaxonal Dystrophy, Late Infantile) 01/2004
1	GM2 Gangliosidoses (GM2 Gangliosidosis) 01/2002

Drug/Important Bio-Agent (IBA)

5	EnzymesIBA 03/2007 - 12/2002
4	alpha-Galactosidase (Beano)IBA 10/2006 - 12/2002
3	LectinsIBA 03/2007 - 06/2004
3	GlycoconjugatesIBA 03/2007 - 01/2004
3	Glycoproteins (Glycoprotein)IBA 04/2006 - 12/2002
2	Mannose (D-Mannose)IBA 03/2007 - 01/2006
2	SugarsIBA 03/2007 - 12/2002
1	Levetiracetam (Keppra)FDA LinkGeneric 05/2015
1	Diazepam (Valium)FDA LinkGeneric 05/2015
1	Pilocarpine (Ocusert)FDA LinkGeneric 05/2015
1	G(M2) Ganglioside (Ganglioside GM2)IBA 03/2007
1	Monoclonal AntibodiesIBA 03/2007
1	Phospholipids (Phosphatides)FDA LinkGeneric 10/2006
1	sialooligosaccharidesIBA 04/2006
1	Cathepsin AIBA 04/2006
1	Neuraminidase (Sialidase)IBA 04/2006
1	Complementary DNA (cDNA)IBA 04/2006
1	Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine AmidaseIBA 04/2006
1	Proteins (Proteins, Gene)FDA Link 04/2006
1	Fluorescein-5-isothiocyanate (FITC)IBA 04/2006
1	beta-Galactosidase (Lactaid)IBA 04/2006
1	5'-deoxy-5'-phosphonomethyladenosine phosphateIBA 04/2006
1	AvidinIBA 04/2006
1	mannose-6-phosphateIBA 01/2006
1	agalsidase beta FDA Link 01/2006
1	Bovine Serum AlbuminIBA 01/2006
1	agalsidase alfaIBA 01/2006
1	Polysaccharides (Glycans)IBA 04/2005
1	Tyrosine (L-Tyrosine)FDA Link 07/2004
1	Tn antigenIBA 01/2004
1	alpha-N-Acetylgalactosaminidase (N-Acetyl-alpha-D-Galactosaminidase)IBA 01/2004
1	Membrane Glycoproteins (Membrane Glycoprotein)IBA 09/2003
1	AntigensIBA 09/2003
1	GangliosidesIBA 02/2003
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 02/2003
1	alpha-Mannosidase (LAMAN)IBA 12/2002
1	beta-N-AcetylhexosaminidasesIBA 01/2002

Therapy/Procedure

4	Enzyme Replacement Therapy 01/2006 - 12/2002
2	Therapeutics 01/2005 - 12/2002